- •Applying acidulated phosphate fluoride gel on fixed orthodontic appliances produces a higher degree of metal corrosion.
- •Acidulated phosphate fluoride gel induced cytotoxic effects in the oral mucosa cells of orthodontic patients.
- •Neutral fluoride gel and varnish use is suggested in orthodontic patients at high risk for caries.
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Funding: This work was supported by the “Lecturer Fund” (DRSZ 6025) from the Faculty of Dentistry, Chulalongkorn University.
Competing interest: Authors have completed and submitted the ICMJE Form for Disclosure of potential conflicts of interest. None declared.
Provenance and peer review: Not commissioned; Externally peer reviewed.