Abstract
Background
Orthodontic tooth movement resulting from coordinated biochemical reactions occurring
in and around cells leads to protein synthesis, mitosis, and cell differentiation.
This study was aimed at comparing the rate of canine retraction as well as the levels
of tumor necrosis factor-α and alkaline phosphatase at specified time intervals during
individual canine retraction using corticotomy-assisted and conventional techniques.
Methods
Twenty patients (10 boys and 10 girls) with a mean age of 14.5 years and requiring
first premolar extractions for orthodontic treatment were included. This split mouth
study was carried out where maxillary canine retraction was done by active tie-backs,
with corticotomy on the experimental side and without corticotomy on the control side.
Rate of retraction was assessed with digital Vernier calipers. Gingival crevicular
fluid samples were collected before starting treatment and at 3 days, 7 days, and
1 month from the distal sides of the canine of both sides after the force was applied.
Results
Minimally invasive corticotomy produced an acceleration in the rate of canine retraction
by approximately 40%. Tumor necrosis factor-α peaked at the third day in both conventional
and corticotomy-assisted canine retraction sides. A gradual increase in the levels
of alkaline phosphatase was observed from baseline to 7 days after corticotomy, which
remained elevated at day 30.
Conclusions
It was concluded that alveolar corticotomy increased rate of canine retraction by
approximately 40%, increased catabolic activities approximately 250%, and increased
anabolic activities approximately 42%.
Keywords
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Article info
Publication history
Published online: November 01, 2018
Accepted:
October 12,
2018
Received:
August 4,
2018
Footnotes
Funding: The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests: Authors have completed and submitted the ICMJE Form for Disclosure of potential conflicts of interest. None declared.
Provenance and peer review: Non-commissioned and externally peer reviewed.
Identification
Copyright
© 2018 World Federation of Orthodontists.
